发明名称 INDANYLAMINOPYRIDYLCYCLOPROPANECARBOXYLIC ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
摘要 The present invention relates to compounds of general formula I, wherein the groups R, R1, R2, R3, m and n are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.
申请公布号 WO2017025368(A1) 申请公布日期 2017.02.16
申请号 WO2016EP68291 申请日期 2016.08.01
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 ECKHARDT, Matthias;PETERS, Stefan;WAGNER, Holger
分类号 C07D213/74;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4436;A61K31/4439;A61K31/444;A61K31/4965;A61K31/506;A61K31/513;A61P3/00;A61P3/04;A61P3/10;C07D401/12;C07D405/12;C07D409/12;C07D413/12 主分类号 C07D213/74
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