| 发明名称 |
METHODS FOR DETECTION AND TREATMENT OF NEURODEGENERATIVE DISEASES |
| 摘要 |
Provided herein are methods for detecting an increased probability or risk of neurodegeneration in a subject. In some embodiments the method comprises assaying a sample from the subject for lysozyme and/or cathepsin S and detecting the lysozyme and/or cathepsin S from the sample, wherein an increased lysozyme and/or cathepsin S compared to levels in a control subject sample indicate an increased probability or risk of neurodegeneration. Methods of treatment and screening assays for determining drug effectiveness are also provided herein. |
| 申请公布号 |
US2017044590(A1) |
申请公布日期 |
2017.02.16 |
| 申请号 |
US201415022928 |
申请日期 |
2014.09.18 |
| 申请人 |
HALDAR Kasturi;ALAM Suhail |
发明人 |
HALDAR Kasturi;ALAM Suhail |
| 分类号 |
C12Q1/37;C12Q1/68;C12Q1/34 |
主分类号 |
C12Q1/37 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for detecting an increased probability or risk of neurodegeneration in a subject comprising assaying a sample from the subject for lysozyme and/or cathepsin S and detecting the lysozyme and/or cathepsin S from the sample, wherein an increased lysozyme and/or cathepsin S compared to levels in a control subject sample indicate an increased probability or risk of neurodegeneration. |
| 地址 |
Chicago IL US |
