MATERIALS WITH MODIFIED SURFACES AND METHODS OF MANUFACTURING

摘要

Various embodiments of surface-modified devices, components, and associated methods of manufacturing are described herein. In one embodiment, an implantable device suitable for being implanted in a patient includes an implantable material having a utile shape and a surface and a modification material deposited on at least a portion of the surface of the implantable material. The modification material has a release rate in an implantation environment in the patient. The modification material at the release rate is effective as bactericidal without being cytotoxic to the patient

主权项

1. An implantable device suitable for being implanted in a patient, comprising:
an implantable material having a utile shape and a surface; and a modification material deposited on at least a portion of the surface of the implantable material, the modification material having a release rate in an implantation environment in the patient, the modification material at the release rate being effective as a bactericidal without being cytotoxic to the patient, wherein the deposited modification material does not substantially affect a mechanical property of the implantable material, and wherein the deposited modification material has an interfacial shear strength of about 1 MPa to about 30 MPa.