发明名称 Method of Treating Lung Adenocarcinoma
摘要 This invention is directed to the treatment of cancer in a patient, particularly a patient with lung adenocarcinoma, and more particularly a patient with SLC34A2-ROS1, CD74-ROS1, or FIG-ROS1 fusion-positive non-small cell lung cancer, with an inhibitor of MET, VEGFR2, and ROS1 which is a compound of Formula (I): or a pharmaceutically acceptable salt thereof.;
申请公布号 US2017042880(A1) 申请公布日期 2017.02.16
申请号 US201515305854 申请日期 2015.04.27
申请人 Exelixis, Inc. 发明人 Aftab Dana T.;Yu Peiwen
分类号 A61K31/47;C12Q1/68 主分类号 A61K31/47
代理机构 代理人
主权项 1. A method for treating lung adenocarcinoma, comprising administering to a patient in need of such treatment a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein: R1 is halo;R2 is halo;R3 is (C1-C6)alkyl;R4 is (C1-C6)alkyl; andQ is CH or N.
地址 South San Francisco CA US