| 发明名称 |
CAPSULE DOSAGE FORM OF METOPROLOL SUCCINATE |
| 摘要 |
This disclosure provides an extended-release capsule dosage form of metoprolol succinate in the form of coated discrete units, wherein said capsule dosage form is bioequivalent to the marketed ToprolXL® tablet. The extended-release capsule dosage form comprising coated discrete units can be sprinkled onto food to ease administration to patients who have difficulty swallowing tablets or capsules. |
| 申请公布号 |
US2017042837(A1) |
申请公布日期 |
2017.02.16 |
| 申请号 |
US201615337611 |
申请日期 |
2016.10.28 |
| 申请人 |
SUN PHARMACEUTICAL INDUSTRIES LIMITED |
发明人 |
VATS Sandeep Kumar;MONDAL Balaram;RAMARAJU Kalaiselvan;SINGH Romi Barat |
| 分类号 |
A61K31/138;A61K9/00;A61K9/48 |
主分类号 |
A61K31/138 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An extended-release capsule dosage form of metoprolol succinate comprising coated discrete units having a d90 value between about 0.2 mm and 1.5 mm, wherein the coated discrete units, after dispersing in an aqueous media for at least 10 minutes, have a desired flowability when passed through a feeding tube and contain not more than 0.50% by weight of the related substances of metoprolol succinate. |
| 地址 |
Mumbai IN |
