发明名称 |
Cyclosporine analogue molecules modified at amino acid 1 and 3 |
摘要 |
Analogues of cyclosporin-A are disclosed comprising modifications of the substituents as the positions of amino acids 1 and 3, according to the following Formula (I). The disclosed compounds include compounds having affinity for cyclophilin, including cyclophilin-A, and reduced immunosuppressivity in comparison with cyclosporin-A and analogs thereof modified solely at position 1. |
申请公布号 |
AU2011342284(B2) |
申请公布日期 |
2017.02.16 |
申请号 |
AU20110342284 |
申请日期 |
2011.12.14 |
申请人 |
ContraVir Pharmaceuticals, Inc. |
发明人 |
Hegmans, Alexander;Fenske, Bruce W.;Trepanier, Dan J.;Abel, Mark D.;Sugiyama, Shin;Ure, Daren R. |
分类号 |
C07K7/64;A61K38/12;A61K38/13;C07K1/113 |
主分类号 |
C07K7/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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