| 发明名称 |
METHODS FOR CROSS-LINKING CORNEAL COLLAGEN WITH VERTEPORFIN FOR THE TREATMENT OF DISORDERS OF THE EYE |
| 摘要 |
Described are compositions and methods of using verteporfin-based photodynamic therapy (PDT) to increase the biomechanical strength of the cornea. More particularly, described herein are compositions and methods for cross-linking collagen in corneal tissue which are useful in the treatment of corneal ectatic disorders. |
| 申请公布号 |
US2017043015(A1) |
申请公布日期 |
2017.02.16 |
| 申请号 |
US201515121909 |
申请日期 |
2015.02.26 |
| 申请人 |
Massachusetts Eye and Ear Infirmary |
发明人 |
ALAGEEL Saleh;CIOLINO Joseph B. |
| 分类号 |
A61K41/00;A61F9/00;A61K9/08;A61N5/06;A61K31/409;A61K9/00 |
主分类号 |
A61K41/00 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method for increasing corneal rigidity in a subject, comprising
topically administering an effective amount of a composition comprising verteporfin to the cornea of a subject in need thereof; and irradiating the cornea with non-thermal laser light. |
| 地址 |
Boston MA US |
