发明名称 |
Combination of Brexpiprazole and Nalmefene and Use Thereof for Treating Substance-Related Disorders |
摘要 |
A medicament comprising (I) brexpiprazole or a pharmaceutically acceptable salt thereof, and (II) nalmefene or a pharmaceutically acceptable salt thereof in combination, wherein brexpiprazole or a pharmaceutically acceptable salt thereof, and nalmefene or a pharmaceutically acceptable salt thereof are contained in a single preparation, or a pharmaceutical composition containing brexpiprazole or a pharmaceutically acceptable salt thereof and a pharmaceutical composition containing nalmefene or a pharmaceutically acceptable salt thereof are formulated for use in combination. The medicament is used for the prophylaxis or treatment of a substance-related disorder, preferably an alcohol-related disorder. |
申请公布号 |
US2017042887(A1) |
申请公布日期 |
2017.02.16 |
申请号 |
US201515305782 |
申请日期 |
2015.04.22 |
申请人 |
OTSUKA PHARMACEUTICAL. CO., LTD. ;H. LUNDBECK A/S |
发明人 |
MAEDA Kenji;NAKAMURA Mai |
分类号 |
A61K31/496;A61K31/485 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
1. A medicament comprising (I) brexpiprazole or a pharmaceutically acceptable salt thereof, and (II) nalmefene or a pharmaceutically acceptable salt thereof in combination, wherein brexpiprazole or a pharmaceutically acceptable salt thereof, and nalmefene or a pharmaceutically acceptable salt thereof are contained in a single preparation, or a pharmaceutical composition containing brexpiprazole or a pharmaceutically acceptable salt thereof and a pharmaceutical composition containing nalmefene or a pharmaceutically acceptable salt thereof are formulated for use in combination. |
地址 |
Tokyo JP |