发明名称 SYNAPTOJANIN-2 INHIBITORS FOR USE IN THE TREATMENT OF CANCER
摘要 Disclosed herein are synaptojanin-2 inhibitors, and novel methods and uses utilizing same for preventing tumor metastasis, treating cancer or inhibiting synaptojanin-2. Compounds disclosed herein include chlorhexidine and pyrvinium, the compound having the formula:;;and compounds characterized by the general formula:;X-L-[(Y)i-(Z)j]-(L-X)k;and/or by the general formula:;;wherein L, X, Y, Z, D, E, i, j and k are as defined herein.
申请公布号 US2017042857(A1) 申请公布日期 2017.02.16
申请号 US201415100322 申请日期 2014.11.27
申请人 YEDA RESEARCH AND DEVELOPMENT CO. LTD. 发明人 YARDEN Yosef;BEN-CHETRIT Nir
分类号 A61K31/353;A61K31/7048;A61K31/7024;A61K31/12;A61K45/06;A61K31/155;A61K31/4709;A61K31/216;A61K31/235;A61K31/05;A61K31/7028;A61K31/7032 主分类号 A61K31/353
代理机构 代理人
主权项
地址 Rehovot IL