METHODS AND SYSTEMS FOR GENERATING A CONDUCTIVITY MAP OF AN IN VIVO TISSUE

摘要

The present disclosure provides methods of generating a conductivity map of an in vivo tissue. The present disclosure provides systems for generating a conductivity map of an in vivo tissue.

主权项

1. A non-invasive method of generating a conductivity map of an in vivo tissue, the method comprising:
a) measuring a concentration of a carrier ion in the tissue using magnetic resonance imaging (MRI); b) measuring a water proton diffusivity (D) in the tissue using diffusion tensor MRI (DT-MRI); and c) generating a conductivity map of the tissue, using the formula:
σ=(D n q2)/kT wherein σ is conductivity, D is the water proton diffusivity, n is the concentration of the carrier ion, q is a charge of the carrier ion, k is Boltzmann constant, and T is temperature in degrees Kelvin.