| 发明名称 |
METHOD FOR MEASURING TOXICITY OF HUMAN CSF |
| 摘要 |
The problem is to provide a method that can quickly and efficiently evaluate the toxicity of human cerebrospinal fluid (CSF) with small amounts of human CSF. The problem is solved by a method comprising administering human CSF into the cerebral ventricle of a rodent such as a mouse, and evaluating the cognitive function of the rodent by using a behavioral pharmacological technique. |
| 申请公布号 |
US2017043039(A1) |
申请公布日期 |
2017.02.16 |
| 申请号 |
US201515304292 |
申请日期 |
2015.04.16 |
| 申请人 |
KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
UCHIDA Shinichi;KANDA Tomoyuki |
| 分类号 |
A61K49/00;A61B5/00;C07K16/18 |
主分类号 |
A61K49/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for measuring the toxicity of human cerebrospinal fluid (hereinafter, “CSF”), comprising
administering human CSF into the cerebral ventricle of a rodent, and evaluating the cognitive function of the rodent by using a behavioral pharmacological technique. |
| 地址 |
Tokyo JP |
