| 发明名称 |
tRNA DERIVED SMALL RNAs (tsRNAs) INVOLVED IN CELL VIABILITY |
| 摘要 |
The present invention features compositions and methods relating to tRNA-derived small RNAs (tsRNAs). Provided herein are oligonucleotide compositions that are complementary to tsRNAs, in particular leuCAGtsRNA, and methods of using the oligonucleotides for the regulation of respective tsRNA. Further provided are methods of inducing apoptosis through the inhibition of leuCAGtsRNA. |
| 申请公布号 |
US2017044530(A1) |
申请公布日期 |
2017.02.16 |
| 申请号 |
US201615216546 |
申请日期 |
2016.07.21 |
| 申请人 |
The Board of Trustees of the Leland Stanford Junior University, Office of the General Counsel |
发明人 |
KAY Mark A.;Kim Hak Kyun;Wang Shengchun |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An oligonucleotide that is complementary to a tRNA-derived small RNA (tsRNA) comprising at least one locked nucleic acid. |
| 地址 |
Stanford CA US |
