发明名称 |
NOVEL ANTI-PD-1 ANTIBODIES |
摘要 |
The present disclosure provides monoclonal antibodies against protein programmed cell death 1 (PD-1), which can block the binding of PD-1 ligands to PD-1, and therefore block the inhibitory function of PD-1 ligands on PD-1 expressing T cells. The antibodies of disclosure provide very potent agents for the treatment of multiple cancers via modulating human immune function. |
申请公布号 |
WO2017024515(A1) |
申请公布日期 |
2017.02.16 |
申请号 |
WO2015CN86594 |
申请日期 |
2015.08.11 |
申请人 |
WUXI BIOLOGICS (CAYMAN) INC.;OPEN MONOCLONAL TECHNOLOGY, INC. |
发明人 |
ZHENG, Yong;LI, Jing;CHEN, Zhisheng |
分类号 |
C07K16/28;A61K39/395;A61P35/00;C12N5/10;C12N15/13;C12N15/63 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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