FORMULATION OF APREPITANT WITH ENHANCED SOLUBILITY
摘要
The solid solution of aprepitant in a polymer, wherein the polymer is the co-polymer of polyvinyl caprolactam with polyvinyl acetate and polyethylene glycol and the weight ratio of aprepitant to the polymer is between 1:4 and 3:7, a process fro the preparation, and the corresponding pharmaceutical compositions and formulations.
申请公布号
EP3129005(A1)
申请公布日期
2017.02.15
申请号
EP20140833503
申请日期
2014.12.23
申请人
Sanofi;Zentiva K.S.
发明人
MATHIEU, Amandine;GRECO, Stephanie;NAKACH, Mostafa;BARDET, Lionel;AUTHELIN, Jean Rene;SKARIA, Cyrus Victor;BERANEK, Josef;DAMMER, Ondrej;KREJCIK, Lukas;CHALUPOVA, Pavla;DUMINIC, Aleksandra