SPIRO[3H-INDOLE-3,2'-PYRROLIDIN]-2(1H)-ONE DERIVATIVES AND THEIR USE AS MDM2-P53 INHIBITORS

摘要

The present invention encompasses compounds of formula (I) wherein the groups R1 to R7, V, W, X, Y, n and q are defined herein, their use as inhibitors of MDM2-p53 interaction, pharmaceutical compositions which contain compounds of this kind, their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases and synthetic intermediates.