发明名称 Proceso para la preparación de diolsulfonas
摘要 The present invention relates to a process for the preparation of a diol sulfone derivative comprising reaction of a halomethyl substrate with a thio-aryl compound to obtain a thio-ether compound, and oxidizing the thio-ether compound to the corresponding sulfone. In case of a chiral halomethyl substrate, the resulting chiral diol sulfone derivative is suitable as a building block for statin type compounds.
申请公布号 ES2601479(T3) 申请公布日期 2017.02.15
申请号 ES20120701093T 申请日期 2012.01.13
申请人 DSM Sinochem Pharmaceuticals Netherlands B.V. 发明人 DE LANGE, Ben;RIEBEL, Peter Hans;WOLBERG, Michael;HEEMSKERK, Dennis;MINK, Daniel
分类号 C07D405/12;C07D413/12;C07D417/12;C07D419/12 主分类号 C07D405/12
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