SERUM ALBUMIN-BINDING FIBRONECTIN TYPE III DOMAINS
摘要
The present invention relates to polypeptides which include tenth fibronectin type III domains (10Fn3) that binds to serum albumin, with south pole loop substitutions. The invention further relates to fusion molecules comprising a serum albumin-binding 10Fn3 joined to a heterologous protein for use in diagnostic and therapeutic applications.
申请公布号
EP3129401(A1)
申请公布日期
2017.02.15
申请号
EP20150714135
申请日期
2015.03.19
申请人
Bristol-Myers Squibb Company
发明人
MITCHELL, Tracy, S.;GOSSELIN, Michael, L.;LIPOVSEK, Dasa;PARKER, Rex;CAMPHAUSEN, Ray;DAVIS, Jonathan;FABRIZIO, David
