| 发明名称 |
METHODS AND COMPOSITIONS FOR PRODUCING DOUBLE ALLELE KNOCK OUTS |
| 摘要 |
The present invention provides a method and compositions utilizing the CRISPR system to disrupt a target gene in eukaryotic cells to produce double allele knock outs. The method finds use in producing afucosylated antibodies with enhanced ADCC activity. |
| 申请公布号 |
EP3022304(A4) |
申请公布日期 |
2017.02.15 |
| 申请号 |
EP20140826452 |
申请日期 |
2014.07.19 |
| 申请人 |
Larix Biosciences LLC |
发明人 |
YU, Bo;LARRICK, James, W. |
| 分类号 |
C12N15/113;C12N15/90 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
