| 摘要 |
The present invention relates to in vitro prognostic method for assessing the risk of death or of liver-related event in a subject, comprising:
a. obtaining at least one, preferably at least 2, of the following variables from the subject:
i. biomarkers measured in a sample from the subject;
ii. clinical data;
iii. binary markers;
iv. blood test results;
b. optionally obtaining at least one blood test result by univariate combination, preferably with a binary logistic regression, of the at least one variable obtained in step (a), said blood test not being a Fibrotest,
c. obtaining at least one physical data from medical imaging or clinical measurement, preferably from elastometry, more preferably from Vibration Controlled Transient Elastography (VCTE), and
d. mathematically combining in a multivariate time-dependent model
- said at least one variable obtained in step (a) and/or said at least one blood test result obtained in step b); and
- said at least one physical data, obtained in step (c)
thereby obtaining a prognostic score. |
