O-DEMETHYLATING PROCESS OF METHOXY SUBSTITUTED MORPHINAN-6-ONE DERIVATIVES
摘要
The present invention relates to an improved process for O-demethylating methoxy substituted morphinan-6-one derivatives using AlCl3 as a demethylating agent in a reaction-inert solvent having a water content ranging from 0.1% wt to 0.8% wt. 10
申请公布号
EP3129383(A1)
申请公布日期
2017.02.15
申请号
EP20150714227
申请日期
2015.04.07
申请人
CILAG AG
发明人
WEIGL, Ulrich, Georg;STÄMPFLI, Dominik, Stefan;MAURER, Nelli
