| 发明名称 | Microorganisms and methods for producing substituted phenols | ||
| 摘要 | The present invention is concerned with methods for producing vanillin, feroyl-CoA, ferulic acid, coniferyl aldehyde and/or coniferyl alcohol. Also, the invention relates to microorganisms useful in such production method, and to the construction of such microorganisms. | ||
| 申请公布号 | US9567618(B2) | 申请公布日期 | 2017.02.14 |
| 申请号 | US201213985261 | 申请日期 | 2012.06.18 |
| 申请人 | SYMRISE AG | 发明人 | Lambrecht Stefan;Hilmer Jens-Michael;Pesaro Manuel;Kroll Jens;Hansen Gunda;Steinbüchel Alexander;Fleige Christian |
| 分类号 | C12N1/12;C12Q1/68;C12N9/04;C12N1/20;C12N15/00;C07H21/04;C12P7/42;C12P1/06;C12P7/00;C12P19/32;C12N9/02;C12P7/22;C12P7/24 | 主分类号 | C12N1/12 |
| 代理机构 | Polsinelli PC | 代理人 | Polsinelli PC |
| 主权项 | 1. A method for producing a product selected from the group consisting of vanillin, feruloyl-CoA, ferulic acid, coniferyl aldehyde and coniferyl alcohol, comprising adding an educt selected from the group consisting of eugenol, coniferyl alcohol, coniferyl aldehyde and ferulic acid to a microorganism of order Actinomycetales and genus Amycolatopsis, wherein the microorganism does not comprise a gene coding for a vanillin dehydrogenase having at least 90% sequence similarity with SEQ ID NO 1, 2, or 3, or comprises an inactivated vanillin dehydrogenase gene having at least 90% sequence similarity with SEQ ID NO 1, 2, or 3. | ||
| 地址 | Holzminden DE | ||