| 发明名称 |
Pharmaceutical composition of doxycycline with reduced food effect |
| 摘要 |
The present invention relates to a once daily pharmaceutical composition comprising doxycycline and one or more pharmaceutically acceptable excipients, wherein the pharmaceutical composition exhibits a reduced food effect. The invention further provides a method of treatment of rosacea by administering to a person in need thereof the doxycycline pharmaceutical composition with or without food. A process of preparing such pharmaceutical composition is also provided. |
| 申请公布号 |
US9566287(B2) |
申请公布日期 |
2017.02.14 |
| 申请号 |
US201615013097 |
申请日期 |
2016.02.02 |
| 申请人 |
Sun Pharmaceutical Industries Limited |
发明人 |
Sharma Ravish Kumar;Metia Pulak Kumar;Singh Ravinder;Shear Rajesh Srikrishan;Fanda Anuj Kumar;Jain Satish Kumar;Singh Romi Barat;Pappu Swarna;Konatham Prabhakar;Katikaneni Pruthvipathy;Jami Dileep |
| 分类号 |
A61K31/65;A61K9/20;A61K9/24 |
主分类号 |
A61K31/65 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A once daily pharmaceutical composition comprising doxycycline and one or more pharmaceutically acceptable excipients, wherein the pharmaceutical composition exhibits a reduced food effect such that the food effect on Cmax is less than 40% and/or AUC0-t is less than 20% as compared to when the pharmaceutical composition is administered in a fasted state. |
| 地址 |
Mumbai IN |
