发明名称 Methods for detecting <i>Ehrlichia </i>infection
摘要 The present invention provides an isolated and purified heat shock protein 60 (Hsp60) peptide having the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to a vaccine against Ehrlichia comprising a peptide homologous to the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to an antibody directed against a peptide homologous to the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to a method of determining whether a subject is infected with Ehrlichia, comprising the steps of: contacting a sample from a subject with the antibody described herein; and detecting a resulting antibody reaction, wherein a positive reaction indicates the subject is infected with Ehrlichia.
申请公布号 US9568473(B2) 申请公布日期 2017.02.14
申请号 US201514851747 申请日期 2015.09.11
申请人 THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 发明人 Walker David H.;Thomas Sunil
分类号 G01N33/53;G01N33/569;A61K39/02;C07K14/29;C07K16/12;A61K38/00;A61K39/00 主分类号 G01N33/53
代理机构 Norton Rose Fulbright US LLP 代理人 Norton Rose Fulbright US LLP
主权项 1. A method for detecting Ehrlichia in a sample comprising the steps of: (a) contacting the sample with an antibody that binds a 21 amino acid peptide having the sequence of SEQ ID NO:2 to form an antibody/peptide complex; and (b) detecting the complex.
地址 Austin TX US