发明名称 |
Methods for detecting <i>Ehrlichia </i>infection |
摘要 |
The present invention provides an isolated and purified heat shock protein 60 (Hsp60) peptide having the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to a vaccine against Ehrlichia comprising a peptide homologous to the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to an antibody directed against a peptide homologous to the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to a method of determining whether a subject is infected with Ehrlichia, comprising the steps of: contacting a sample from a subject with the antibody described herein; and detecting a resulting antibody reaction, wherein a positive reaction indicates the subject is infected with Ehrlichia. |
申请公布号 |
US9568473(B2) |
申请公布日期 |
2017.02.14 |
申请号 |
US201514851747 |
申请日期 |
2015.09.11 |
申请人 |
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
Walker David H.;Thomas Sunil |
分类号 |
G01N33/53;G01N33/569;A61K39/02;C07K14/29;C07K16/12;A61K38/00;A61K39/00 |
主分类号 |
G01N33/53 |
代理机构 |
Norton Rose Fulbright US LLP |
代理人 |
Norton Rose Fulbright US LLP |
主权项 |
1. A method for detecting Ehrlichia in a sample comprising the steps of:
(a) contacting the sample with an antibody that binds a 21 amino acid peptide having the sequence of SEQ ID NO:2 to form an antibody/peptide complex; and (b) detecting the complex. |
地址 |
Austin TX US |