| 发明名称 | <i>Plasmodium </i>diagnostic assay device | ||
| 摘要 | This invention relates to assays for a Plasmodium analyte in a liquid sample such as a body fluid. More particularly, the invention relates to a method and apparatus for the detection of a ligand in a body fluid such as urine or blood, which can diagnose malarial infection. | ||
| 申请公布号 | US9568471(B2) | 申请公布日期 | 2017.02.14 |
| 申请号 | US200611883130 | 申请日期 | 2006.01.25 |
| 申请人 | The Johns Hopkins University | 发明人 | Sullivan David J.;Scholl Peter |
| 分类号 | C12Q1/44;C12Q1/02;C12Q1/32;G01N33/569 | 主分类号 | C12Q1/44 |
| 代理机构 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. | 代理人 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Corless Peter F.;Emmons Richard B. |
| 主权项 | 1. A method of diagnosing a Plasmodium falciparum infection in a human subject using an immunoassay, the method comprising contacting a urine sample obtained from the subject with the monoclonal antibody 3A4 deposited as PTA-123432 or the monoclonal antibody 4A5 deposited as PTA-123433, wherein the monoclonal antibody binds to histidine rich protein II (HRP II) and/or HRP III of Plasmodium falciparum and detects the presence of the HRP II and/or the HRP III in the urine, thereby diagnosing the Plasmodium falciparum infection in the human subject. | ||
| 地址 | Baltimore MD US | ||