发明名称 |
Oral pharmaceutical composition of aliphatic amine polymer or salts thereof |
摘要 |
The present invention relates to an oral pharmaceutical composition of aliphatic amine polymer or salts thereof comprising mixture of water and organic solvent(s) and/or less than of about 10% of plasticizing agent in the coating composition. In particular, present invention relates to a coated pharmaceutical composition of aliphatic amine polymer or salt thereof which comprises mixture of water and organic solvent(s) and less than of about 10% of plasticizing agent in coating. The invention also includes process of preparing such composition. |
申请公布号 |
US9566299(B2) |
申请公布日期 |
2017.02.14 |
申请号 |
US201414766327 |
申请日期 |
2014.02.05 |
申请人 |
WOCKHARDT LIMITED |
发明人 |
Jain Girish Kumar;Naidu Venkataramana;Khan Abdul Rehman;Agarwal Amar;Pattipati Srikanth |
分类号 |
A61K9/28;A61K31/785 |
主分类号 |
A61K9/28 |
代理机构 |
Bio Intellectual Property Services LLC (Bio IPS) |
代理人 |
Bio Intellectual Property Services LLC (Bio IPS) ;Zaghmout O. (Sam) |
主权项 |
1. An oral pharmaceutical composition comprising
a) a core comprising colesevelam hydrochloride in an amount of 625 mg and b) a coating layer coated over said core (a) with a coating composition comprising, (i) di-acetylated monoglyceride in an amount of 2.25 mg, (ii) hydroxypropylmethylcellulose (HPMC) 15 Cp in an amount of 49.28 mg per tablet, (iii) hydroxypropylmethylcellulose (HPMC) 5 Cp in an amount of 49.28 mg per tablet, and (iv) mixture of water and isopropyl alcohol in the ratio of about 90:10 to about 10:90. |
地址 |
Bandra East, Mumbai IN |