| 发明名称 | Compositions and methods for inhibition of the JAK pathway | ||
| 摘要 | Disclosed are compounds of formula I, compositions containing them, and methods of use for the compounds and compositions in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK 2 and JAK3, are therapeutically useful. | ||
| 申请公布号 | US9566283(B2) | 申请公布日期 | 2017.02.14 |
| 申请号 | US201514793506 | 申请日期 | 2015.07.07 |
| 申请人 | Rigel Pharmaceuticals, Inc. | 发明人 | Chen Yan;Taylor Vanessa;Li Hui;Singh Rajinder |
| 分类号 | A01N43/54;A61K31/505;A61K31/5415;A61K31/155;C07D401/14;C07D403/12;C07D413/04;C07D487/08;A61K31/506;A61K31/5377;A61K31/5383;A61K31/54;A61K31/541;A61K31/551;A61K45/06;C07D413/12;C07D419/14;C07D471/08;C07D487/04;C07D491/08;A61K31/538;A61K31/55;A61K31/675;C07D413/14;C07D471/04;C07D487/10;C07D498/04;C07F9/6558 | 主分类号 | A01N43/54 |
| 代理机构 | Klarquist Sparkman, LLP | 代理人 | Young, J.D. Travis;Klarquist Sparkman, LLP |
| 主权项 | 1. A method, comprising administering to a subject an amount of 5-(2-(4-fluoro-3-methoxy-5-methylphenylamino)-5-methylpyrimidin-4-ylamino)benzo[d]oxazol-2(3H)-one, or a salt thereof, or a composition compromising 5-(2-(4-fluoro-3-methoxy-5-methylphenylamino)-5-methylpyrimidin-4-ylamino)benzo[d]oxazol-2(3H)-one or salt thereof, effective to contact a JAK kinase and inhibit a property thereof. | ||
| 地址 | South San Francisco CA US | ||