The invention concerns derivatives of CMAP27, which have a good antimicrobial activity and a low haemolytic activity as compared to the wild-type CMAP27 peptide. These derivatives can be used for antibiotic therapy or in a bacteriocidal composition. Further comprised in the invention is the use of CMAP27 and/or its derivatives as adjuvant.
申请公布号
DK2396345(T3)
申请公布日期
2017.02.13
申请号
DK20100704016T
申请日期
2010.02.12
申请人
Universiteit Utrecht Holding B.V.
发明人
Bikker, Floris Jacob;VAN DIJK, Albert;MARS-GROENENDIJK, Rosalia;VELDHUIZEN, Edwin Johannes Adrianus;VAN DER KLEIJ, Desiree;HAAGSMAN, Hendrik;MOLHOEK, Elisabeth Margarita