发明名称 |
FREMGANGSMÅDE TIL FREMSTILLING AF VACCINESAMMENSÆTNING |
摘要 |
A method of preparing a composition comprising one or more antigens adsorbed to an amino acid wherein said method comprises: (i) mixing a solution of one or more antigens with a solution of the amino acid in an aqueous acid whilst neutralising the mixture of solutions, thereby forming an adsorbate comprising the one or more antigens and the amino acid; (ii) separating the adsorbate into a desired buffer by cross-flow filtration thereby forming said composition; and (iii) recovering said composition; wherein steps (i) to (iii) are performed in a sterile environment and within a closed system. |
申请公布号 |
DK2699255(T3) |
申请公布日期 |
2017.02.13 |
申请号 |
DK20120719034T |
申请日期 |
2012.04.20 |
申请人 |
Allergy Therapeutics (UK) Limited |
发明人 |
SKINNER, Murray;HEWINGS, Simon;PACKER, Duncan;POLAND, Richard |
分类号 |
A61K9/14;A61K39/00;A61K39/36 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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