| 发明名称 |
ENGINEERED ENZYME FOR ENZYME REPLACEMENT THERAPY |
| 摘要 |
An engineered enzyme, comprising an amino acid sequence that is at least 80% identical to the amino acid sequence of a human beta-glucuronidase, wherein the engineered enzyme exhibits a higher level of alpha-iduronidase enzymatic activity as compared to the human beta-glucuronidase. |
| 申请公布号 |
WO2017024204(A1) |
申请公布日期 |
2017.02.09 |
| 申请号 |
WO2016US45715 |
申请日期 |
2016.08.05 |
| 申请人 |
ROFFLER, Steve;ACADEMIA SINICA |
发明人 |
ROFFLER, Steve;CHUANG, Huai-Yao |
| 分类号 |
C12N9/24;A61K38/47;C12N15/52;C12Q1/34 |
主分类号 |
C12N9/24 |
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