METHODS AND KITS FOR DETERMINING A PERSONALIZED TREATMENT REGIMEN FOR A SUBJECT SUFFERING FROM A PATHOLOGIC DISORDER

摘要

The invention relates to methods and kits for determining and optimizing a personalized treatment regimen for a subject suffering from a pathologic disorder based on calculating the value of M, that indicates the ability of said subject to eliminate said disorder. The invention specifically relates to optimization of interferon treatment of viral disorders.

主权项

1. A method for determining a personalized treatment regimen for a subject suffering from a pathologic disorder, said method comprises the step of:
a. calculating the value of M, wherein said value indicates the ability of said subject to eliminate said disorder; b. determining the value of M1, said value indicates the minimal ability required for eliminating said disorder; c. providing the dose A1 and number B1 of administrations of said dose to obtain an amount C1 of said medicament required for eliminating said disorder in subjects having a value of M that is equal or above said M1 value, wherein A1*B1=C1; and d. calculating the dose A and number B of administrations of said dose A to obtain an amount C1 required for said subject having said M determined/calculated in step (a), wherein said A=A1/(M1/M) and B=B1*(M1/M); thereby at least one of determining and optimizing the treatment regimen for said subject.