发明名称 BIOLOGICALLY-RELEVANT SELECTIVE ENCLOSURES FOR PROMOTING GROWTH AND VASCULARIZATION
摘要 Two-dimensional materials, particularly graphene-based materials, having a plurality of apertures therein can be formed into enclosures for various substances and a fibrous layer can be provided on an outside and/or on an inside of the enclosure. The enclosures can be exposed to an environment, such as a biological environment (in vivo or in vitro), where the fibrous layer can promote vascular ingrowth. One or more substances within the enclosure can be released into the environment, one or more selected substances from the environment can enter the enclosure, one or more selected substances from the environment can be prevented from entering the enclosure, one or more selected substances can be retained within the enclosure, or combinations thereof. The enclosure can, for example, allow a sense-response paradigm to be realized. The enclosure can, for example, provide immunoisolation for materials, such as living cells, retained therein.
申请公布号 US2017037356(A1) 申请公布日期 2017.02.09
申请号 US201615099276 申请日期 2016.04.14
申请人 Lockheed Martin Corporation 发明人 Simon Sarah M.;Sinsabaugh Steven Lloyd;Swett Jacob Louis
分类号 C12M1/34;C12M1/12;C12M1/00 主分类号 C12M1/34
代理机构 代理人
主权项 1. An enclosure comprising a compartment and a wall separating the compartment from an environment external to the compartment, wherein the wall comprises: a perforated graphene-based material layer and a substrate layer affixed directly or indirectly to the perforated graphene-based material.
地址 Bethesda MD US