发明名称 |
DOPAMINERGIC MIMETICS |
摘要 |
A method is described for providing acute symptomatic relief to a subject with Parkinson's Disease (PD) or other CNS disorders resulting from dopamine deficiency in the brain comprising administering to said subject an amount of a ketogenic material sufficient to produce a ketosis in the subject sufficient to provide therapeutic benefit in such neurological disorders. Preferred materials produce a ketosis is such that the total concentration of acetoacetate and (R)-3-hydroxybutyrate in the blood of the subject is raised to between 0.1 and 30 mM. |
申请公布号 |
US2017035712(A1) |
申请公布日期 |
2017.02.09 |
申请号 |
US201514875999 |
申请日期 |
2015.10.06 |
申请人 |
BTG International Limited |
发明人 |
MARTIN Keith Frank;HEAL David John |
分类号 |
A61K31/19 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
1. A method of providing acute symptomatic relief to a subject in need of acute therapy for CNS disorders resulting from dopamine deficiency in the brain comprising administering to said subject a therapeutically effective dose of a ketogenic material. |
地址 |
London GB |