TRANSDERMAL ABSORPTION SHEET AND METHOD OF MANUFACTURING TRANSDERMAL ABSORPTION SHEET

摘要

To provide a transdermal absorption sheet with which control of a dissolution rate and suppression of drug diffusion can be achieved, and a method of manufacturing the transdermal absorption sheet. A transdermal absorption sheet 100 is provided with a sheet portion 116, a plurality of frustum portions 114 that is disposed on the sheet portion 116, and needle portions 112 that are disposed on the frustum portions 114, each of the plurality of needle portions 112 includes a first layer 120 containing a drug and a second layer 122 not containing a drug, and at least one of the plurality of needle portions 112 contains an air bubble 124.

主权项

1. A transdermal absorption sheet comprising:
a fiat plate-shaped sheet portion; a plurality of frustum portions which are disposed on the sheet portion and in each of which a larger bottom surface is connected to the sheet portion; and a plurality of tapered-shaped needle portions which are disposed on the plurality of frustum portions and in each of which a bottom surface is connected to a smaller bottom surface of the frustum portion, wherein each of the plurality of needle portions includes a first layer containing a predetermined amount of a drug and a second layer not containing a predetermined amount of a drug, and at least one of the plurality of needle portions contains an air bubble.