发明名称 |
Prevention of disulfide bond reduction during recombinant production of polypeptides |
摘要 |
The invention concerns methods and means for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide 5 containing polypeptides, including antibodies, from recombinant host cell cultures. 4233238_1 (GHMatters) P82944.AU.1 |
申请公布号 |
AU2013203411(C9) |
申请公布日期 |
2017.02.09 |
申请号 |
AU20130203411 |
申请日期 |
2013.04.10 |
申请人 |
GENENTECH, INC. |
发明人 |
KAO, Yung-Hsiang;SCHMIDT, Melody Trexler;LAIRD, Michael W.;WONG, Rita L.;HEWITT, Daniel P. |
分类号 |
C07K1/00;C07K14/00 |
主分类号 |
C07K1/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|