| 发明名称 |
GROUP A STREPTOCOCCUS VACCINE |
| 摘要 |
A method and composition for eliciting an immune response to group A streptococcal bacteria in a mammal is provided, which includes administering to the mammal an M protein fragment, variant or derivative thereof and a SpyCEP protein or peptide fragment, or an antibody to the SpyCEP protein or fragment to facilitate restoring or enhancing neutrophil activity. Also provided is an immunodominant peptide fragment of SpyCEP. |
| 申请公布号 |
US2017037087(A1) |
申请公布日期 |
2017.02.09 |
| 申请号 |
US201515304462 |
申请日期 |
2015.04.15 |
| 申请人 |
Griffith University |
发明人 |
Pandey Manisha;Batzloff Michael;Good Michael |
| 分类号 |
C07K14/315;C07K16/12;A61K38/48;C07K16/40;A61K39/09;A61K39/395 |
主分类号 |
C07K14/315 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of eliciting an immune response to group A streptococcal bacteria in a mammal, said method including the step of administering to the mammal: an M protein fragment, variant or derivative thereof; and an agent that facilitates restoring or enhancing neutrophil activity; to thereby elicit an immune response to group A streptococcal bacteria in the mammal. |
| 地址 |
Nathan, Queensland AU |
