| 发明名称 |
NOVEL COMPOSITION FOR TREATMENT OF ESSENTIAL THROMBOCYTHEMIA |
| 摘要 |
The present invention relates to a novel pharmaceutical composition free of gastric coating comprising anagrelide hydrochloride in combination with a non-pH dependent polymer and a pharmaceutically acceptable watersoluble acid and its use for the treatment of essential thrombocythemia. |
| 申请公布号 |
US2017035768(A1) |
申请公布日期 |
2017.02.09 |
| 申请号 |
US201615331798 |
申请日期 |
2016.10.21 |
| 申请人 |
AOP ORPHAN PHARMACEUTICALS AG |
发明人 |
WIDMANN Rudolf;STRIEDER Georg |
| 分类号 |
A61K31/519;A61K9/20;A61K47/38;A61K47/12;A61K9/16;A61K47/32 |
主分类号 |
A61K31/519 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition free of gastric coating comprising anagrelide HCl, a non-pH dependent polymer and a pharmaceutically acceptable water soluble acid, wherein the non-pH dependent polymer is selected from the group consisting of a polyacrylacid, a cellulose derivative, and a polyacrylamide, and wherein the amount of the non-pH dependent polymer is between 1.5 and 2.5 fold of the anagrelide (w/w). |
| 地址 |
Vienna AT |
