发明名称 |
A METHOD FOR DETECTION OF PRESENCE OR ABSENCE OF ANALYTES IN FLUIDS AND AN OPTICAL DETECTION SYSTEM FOR CARRYING OUT THE METHOD |
摘要 |
A method and a system for detection of presence or absence of analytes in fluids, the method comprising the steps of: a) contacting a fluid sample and a plurality of nanoparticles, the nanoparticles being functionalized with a selective ligand, the contact of the fluid sample with the nanoparticles being under conditions such that, the nanoparticles aggregate selectively on surface of their target analyte, forming a nanoparticle-analyte complex, the aggregation promoting the concentration of the nanoparticles on the surface of the target analyte; b) subjecting a fluid mixture of the fluid sample and the plurality of nanoparticles to SERS; c) measuring at least a SERS signal associated with the fluid mixture; d) spectrally analysing the at least one SERS signal of step c); e) recognizing at least one defined SERS spectrum of the nanoparticle-analyte complex, through a SERS signal enhanced by the at least one narrow inter-nanoparticle gap. |
申请公布号 |
WO2017020936(A1) |
申请公布日期 |
2017.02.09 |
申请号 |
WO2015EP67717 |
申请日期 |
2015.07.31 |
申请人 |
MEDCOM ADVANCE, S.A;UNIVERSITAT ROVIRA I VIRGILI;FUNDACIO PRIVADA CENTRE TECNOLOGIC DE LA QUIMICA DE CATALUNYA;FUNDACIO PRIVADA INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANÇATS;MEDCOM TECH, S.A. |
发明人 |
PAZOS-PEREZ, Nicolas;PAZOS, Elena;CATALA, Carme;MIR-SIMON, Bernat;GOMEZ-DE-PEDRO, Sara;SAGALES, Juan;VILLANUEVA, Carlos;ALVAREZ-PUEBLA, Ramon A. |
分类号 |
G01N21/65;B82Y15/00;C12Q1/04 |
主分类号 |
G01N21/65 |
代理机构 |
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