发明名称 |
1,1,1-TRIFLUORO-3-HYDROXYPROPAN-2-YL CARBAMATE DERIVATIVES AND 1,1,1-TRIFLUORO-4-HYDROXYBUTAN-2-YL CARBAMATE DERIVATIVES AS MAGL INHIBITORS |
摘要 |
The present invention provides, in part, compounds of Formula I and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating MAGL-mediated diseases and disorders including, e.g., pain, an inflammatory disorder, traumatic brain injury, depression, anxiety, Alzheimer's disease, a metabolic disorder, stroke, or cancer. |
申请公布号 |
WO2017021805(A1) |
申请公布日期 |
2017.02.09 |
申请号 |
WO2016IB54266 |
申请日期 |
2016.07.18 |
申请人 |
PFIZER INC. |
发明人 |
BECK, Elizabeth Mary;BRODNEY, Michael Aaron;BUTLER, Christopher Ryan;GILBERT, Adam Matthew;HELAL, Christopher John;JOHNSON, Douglas Scott;MCALLISTER, Laura Ann;MONTGOMERY, Justin Ian;O'NEIL, Steven Victor;ROGERS, Bruce Nelsen;VERHOEST, Patrick Robert;WEBB, Damien |
分类号 |
C07D401/14;C07D401/04;C07D401/12;C07D405/12;C07D405/14;C07D413/14;C07D471/10;C07D493/10;C07D498/10;C07D515/10 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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