This invention relates to a novel chemical process for the synthesis of N'-benzyl-5- methylisoxazole-3-carbohydrazide (Isocarboxazid) which comprises reacting 5-methyl-3- isoxazole carboxylic acid ester with benzylhydrazine or a salt thereof in an aprotic organic solvent and in the presence of an organic base.
申请公布号
WO2017021246(A1)
申请公布日期
2017.02.09
申请号
WO2016EP67868
申请日期
2016.07.27
申请人
LUNDBECK PHARMACEUTICALS ITALY S.P.A.
发明人
DE FAVERI, Carla;HUBER, Florian, Anton, Martin;ANTOLINI, Nicola
