| 发明名称 |
METHODS TO INDUCE CONVERSION OF REGULATORY T CELLS INTO EFFECTOR T CELLS FOR CANCER IMMUNOTHERAPY |
| 摘要 |
Provided by the disclosure are methods for modulating differentiation of regulatory T cells (e.g., CD4+ or CD8+ regulatory T cells). In some embodiments, methods include contacting regulatory T cells with an agent that decreases Helios activity and/or Helios expression. |
| 申请公布号 |
WO2016196912(A8) |
申请公布日期 |
2017.02.09 |
| 申请号 |
WO2016US35692 |
申请日期 |
2016.06.03 |
| 申请人 |
DANA-FARBER CANCER INSTITUTE, INC. |
发明人 |
CANTOR, Harvey;KIM, Hye-Jung |
| 分类号 |
A61K39/39;A61K39/395;A61P35/00;A61P37/00;G01N33/50 |
主分类号 |
A61K39/39 |
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