| 发明名称 |
ISOLATION AND PURIFICATION OF 6-AMINOCAPROIC ACID |
| 摘要 |
The present invention relates to a new process for the isolation and purification of 6-aminocaproic acid, which is a known inhibitor of enzymes responsible for fibrinolysis and is used in the treatment of coagulopathies and severe post-operative bleedings. |
| 申请公布号 |
US2017036991(A1) |
申请公布日期 |
2017.02.09 |
| 申请号 |
US201615228122 |
申请日期 |
2016.08.04 |
| 申请人 |
DIPHARMA FRANCIS S.r.l. |
发明人 |
MAGNANI Massimo;BRUNOLDI Enrico;RAZZETTI Gabriele;RESTELLI Alessandro |
| 分类号 |
C07C227/40;C07C229/08;C07C227/42 |
主分类号 |
C07C227/40 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process for isolating 6-aminocaproic acid of formula (I), comprising forming a mixture of an addition salt of 6-aminocaproic acid of formula (Ia) with a protic acid, in a solvent, wherein HX is a protic acid, converting said salt into 6-aminocaproic acid of formula (I) by treatment with an organic base in a solvent, and recovering the 6-aminocaproic acid of formula (I) from said mixture. |
| 地址 |
Baranzate (MI) IT |
