| 发明名称 |
COMPOSITIONS OF OBETICHOLIC ACID AND METHODS OF USE |
| 摘要 |
The disclosure relates to obeticholic acid formulations with improved stability, dissolution, and/or solubility, methods of preparing the same for use and methods of treating various diseases and conditions. |
| 申请公布号 |
US2017035784(A1) |
申请公布日期 |
2017.02.09 |
| 申请号 |
US201615139138 |
申请日期 |
2016.04.26 |
| 申请人 |
Intercept Pharmaceuticals, Inc. ;Sumitomo Dainippon Pharma Co., Ltd. |
发明人 |
Lancaster Richard Gail;Olmstead Kay K.;Kagihiro Masashi;Matono Mitsuhiro;Taoka Ikuko;Pruzanski Mark;Shapiro David;Hooshmand-Rad Roya;Pencek Richard;Sciacca Cathi;Eliot Lise;Edwards Jeffrey;MacConell Leigh A.;Marmon Tonya K. |
| 分类号 |
A61K31/575;A61K45/06;A61K9/20 |
主分类号 |
A61K31/575 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising obeticholic acid, or a pharmaceutically acceptable salt, ester, or amino acid conjugate thereof, wherein obeticholic acid or a pharmaceutically acceptable salt, ester, or amino acid conjugate thereof is in the form of particles, and wherein at least 50% of the particles have a diameter of 200 μm or less. |
| 地址 |
New York NY US |
