发明名称 Phenyl tetrahydroisoquinoline compound substituted with heteroaryl
摘要 Provided is a compound represented by formula [1] that has excellent NHE3 inhibitory effects, or a pharmaceutically acceptable salt thereof. (In formula [1], A indicates a structure represented by formula [2]. In formula [2], R11 and R12 represent a halogen atom or the like, R2 indicates a C1-6 alkyl or the like, ring E indicates a triazole, a tetrazole, a pyrimidine or the like, R31 and R32 represent a hydrogen atom, a C1-6 alkyl, a C1-6 alkoxy or the like, and W indicates a single bond, a formula –NH–, a formula –O–, or a formula –CONH–. Y indicates a hydrogen atom or a structure represented by formula [3'].)
申请公布号 AU2015293134(A1) 申请公布日期 2017.02.09
申请号 AU20150293134 申请日期 2015.07.24
申请人 Taisho Pharmaceutical Co., Ltd. 发明人 Kuroda, Shoichi;Kawabe, Kenichi;Ushiki, Yasunobu;Ohta, Hiroshi;Uneuchi, Fumito;Shibata, Tsuyoshi;Tabuse, Hideaki;Munetomo, Eiji;Chonan, Sumi
分类号 C07D401/10;A61K31/4725;A61P1/10;A61P43/00;C07D401/14;C07D403/14;C07D405/10;C07D413/10;C07D413/14;C07D417/10 主分类号 C07D401/10
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