发明名称 |
Phenyl tetrahydroisoquinoline compound substituted with heteroaryl |
摘要 |
Provided is a compound represented by formula [1] that has excellent NHE3 inhibitory effects, or a pharmaceutically acceptable salt thereof. (In formula [1], A indicates a structure represented by formula [2]. In formula [2], R11 and R12 represent a halogen atom or the like, R2 indicates a C1-6 alkyl or the like, ring E indicates a triazole, a tetrazole, a pyrimidine or the like, R31 and R32 represent a hydrogen atom, a C1-6 alkyl, a C1-6 alkoxy or the like, and W indicates a single bond, a formula –NH–, a formula –O–, or a formula –CONH–. Y indicates a hydrogen atom or a structure represented by formula [3'].) |
申请公布号 |
AU2015293134(A1) |
申请公布日期 |
2017.02.09 |
申请号 |
AU20150293134 |
申请日期 |
2015.07.24 |
申请人 |
Taisho Pharmaceutical Co., Ltd. |
发明人 |
Kuroda, Shoichi;Kawabe, Kenichi;Ushiki, Yasunobu;Ohta, Hiroshi;Uneuchi, Fumito;Shibata, Tsuyoshi;Tabuse, Hideaki;Munetomo, Eiji;Chonan, Sumi |
分类号 |
C07D401/10;A61K31/4725;A61P1/10;A61P43/00;C07D401/14;C07D403/14;C07D405/10;C07D413/10;C07D413/14;C07D417/10 |
主分类号 |
C07D401/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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