| 发明名称 |
SOLUBLE HIV-1 ENVELOPE GLYCOPROTEIN TRIMERS |
| 摘要 |
The present application relates to novel HIV-1 envelope glycoproteins which may be utilized as an HIV-1 vaccine immunogens, antigens for crystallization and for the identification of broad neutralizing antibodies. The present invention encompasses the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention. |
| 申请公布号 |
US2017035877(A1) |
申请公布日期 |
2017.02.09 |
| 申请号 |
US201414508369 |
申请日期 |
2014.10.07 |
| 申请人 |
International AIDS Vaccine Initiative ;The Scripps Research Institute |
发明人 |
Wyatt Richard;Ward Andrew;Tran Karen;Kumar Shailendra;Ingale Jidnyasa;Guenaga Javier;Feng Yu;Dubrowskaya Viktoria;de Val Alta Natalia |
| 分类号 |
A61K39/21;C07K14/005;C12N7/00 |
主分类号 |
A61K39/21 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An engineered or non-naturally occurring JRFL SOSIP trimer. |
| 地址 |
New York NY US |
