Methods and uses are provided for inducing an immune response comprising at least two administrations of an immunogenic composition, wherein a lower dose is given in the second administration than in the first administration, and wherein the second administration may be unadjuvanted.
申请公布号
EP3125930(A1)
申请公布日期
2017.02.08
申请号
EP20150713531
申请日期
2015.04.02
申请人
GlaxoSmithKline Biologicals S.A.
发明人
BALLOU JR, William Ripley;DEMOITIE, Marie-Ange;DONNER, Marie-Noelle Renelle;OUAKED, Nadia;TEMMERMAN, Stephane Theophile