发明名称 |
RARE CLONOTYPES AND USES THEREOF |
摘要 |
The invention is directed to a method of selecting disease-correlated clonotypes that have a reduced likelihood of producing a false positive signal of relapse when used to monitor minimal residual disease. In accordance with the invention, candidate correlating clonotypes are obtained from a patient, the rarity of each is determined either by comparison with a clonotype database or a clonotype model, and one or more of the rarest of such clonotypes are used to monitor the minimal residual disease. |
申请公布号 |
EP2959020(A4) |
申请公布日期 |
2017.02.08 |
申请号 |
EP20140754622 |
申请日期 |
2014.02.20 |
申请人 |
Adaptive Biotechnologies Corporation |
发明人 |
PEPIN, Francois;FAHAM, Malek;MOORHEAD, Martin |
分类号 |
C12Q1/68;G01N33/48 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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