发明名称 |
HIGH SENSITIVE DETECTION OF MELATONIN |
摘要 |
The present invention relates to the use of a derivative of melatonin in an assay, wherein said derivative is a conjugate at position 3 of melatonin's indole ring and wherein said conjugate comprises a linker of at least 2 carbon atoms, with the proviso that the conjugate does not comprise a polypeptide or protein antigen. The derivative preferably comprises 3-(2-ethylamidoglutaric acid)-5-methoxyindole (GUS) and is coupled to a carrier such as dextran. The invention further relates to a method for detecting and/or quantifying melatonin in a sample using a compound comprising said derivative of melatonin, a corresponding immunobiological assay and a kit of parts for detecting and/or quantifying melatonin based on the melatonin derivative. |
申请公布号 |
EP3126838(A1) |
申请公布日期 |
2017.02.08 |
申请号 |
EP20150741886 |
申请日期 |
2015.04.01 |
申请人 |
Koninklijke Philips N.V. |
发明人 |
VAN ROOSMALEN, Markus Hendrikus |
分类号 |
G01N33/532;C07D209/16;G01N33/535;G01N33/543;G01N33/74 |
主分类号 |
G01N33/532 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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