发明名称 |
POLYMUTANT TAU PROTEIN VARIANTS AND THEIR USE FOR RECAPITULATING HUMAN TAUOPATHIES |
摘要 |
Disclosed herein are methods for identifying an agent for treating or preventing neurogenerative disease and to methods for recapitulating tauopathies using a tau protein that includes at least four different mutations that cause the condition frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), and to nucleic acids encoding the tau protein. |
申请公布号 |
EP2702073(B1) |
申请公布日期 |
2017.02.08 |
申请号 |
EP20110716418 |
申请日期 |
2011.04.28 |
申请人 |
Universität Leipzig |
发明人 |
ROBITZKI, Andrea;JAHNKE, Heinz-Georg;KRINKE, Dana;STRIGGOW, Frank;MACK, Till |
分类号 |
C07K14/47 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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