发明名称 |
INTEGRATED MICROFLUIDIC DEVICE FOR TARGET AMPLIFICATION AND MICROARRAY DETECTION |
摘要 |
In one aspect, the present disclosure provides an integrated microfluidic device for nucleic acid amplification and microarray detection. In one aspect, the device comprises: (1) a microchip configured to process reagents, comprising a plurality of reservoirs, channels, valves, and/or fluid interfaces; (2) an amplification chamber for PCR, carried out in a detachable tube assembled on the microchip through a joint; and (3) a microarray chamber comprising a microarray and a reaction chamber. In some embodiments, these features are interconnected to allow transportation of reagents for nucleic acid amplification and hybridization detection functions in a closed system. In one aspect, the integrate device herein overcomes the problem of contamination during the amplification and hybridization reactions. |
申请公布号 |
EP3126485(A1) |
申请公布日期 |
2017.02.08 |
申请号 |
EP20150774049 |
申请日期 |
2015.03.31 |
申请人 |
CapitalBio Corporation;Tsinghua University |
发明人 |
LIU, Yan;ZHANG, Guohao;ZHU, Jiang;FENG, Zhengde;GUO, Hongju;GAO, Jian;XING, Wanli;CHENG, Jing |
分类号 |
C12M1/34;C12M1/00 |
主分类号 |
C12M1/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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