发明名称 |
AMIDO-SUBSTITUTED AZOLE COMPOUNDS |
摘要 |
The present invention relates to amido-substituted azole compounds of general formula (I), in which X1, X2, R1, R2, R4, R5, R7 and R8 are as defined in the claims which are inhibitors of TNKS1 and/or TNKS2, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients. |
申请公布号 |
EP3126337(A2) |
申请公布日期 |
2017.02.08 |
申请号 |
EP20150741893 |
申请日期 |
2015.04.01 |
申请人 |
Bayer Pharma Aktiengesellschaft |
发明人 |
EIS, Knut;ACKERSTAFF, Jens;WAGNER, Sarah;BASTING, Daniel;GOLZ, Stefan;BENDER, Eckhard;LI, Volkhart Min-Jian;LIENAU, Philip;LIU, Ningshu;SIEGEL, Franziska;BAUSER, Marcus;SÜLZLE, Detlev;HOLTON, Simon;BAIRLEIN, Michaela;BUCHGRABER, Philipp;BÁLINT, József |
分类号 |
C07D233/90;A61K31/4164;A61K31/421;A61K31/4439;A61K31/454;A61K31/496;A61K31/5377;A61P35/00;A61P35/02;C07D263/34;C07D295/092;C07D401/12;C07D403/12;C07D413/06;C07D491/107 |
主分类号 |
C07D233/90 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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